Amino Acid Imbalance in Atherosclerosis _ Crimson Publishers

Amino Acid Imbalance in Atherosclerosis by Nefyodov LI in Integrative Journal of Conference Proceedings


A review of literature data on the mechanisms of formation of the stock of free amino acids and their derivatives in atherosclerosis and methods for correcting metabolic imbalance.

Our special interest in the study of the role of amino acids in the pathogenesis, prevention and treatment of atherosclerosis and its accompanying cardiovascular pathology in circulatory failure is due to several reasons. So, atherosclerosis is characterized not only by disturbances in the metabolic flows of carbohydrate (inhibition of gluconeogenesis and activation of glycolysis), lipid (activation of lipolysis, ketosis), but also protein (proteinand hypoalbuminemia), hyperglobulinemia and negative nitrogen balance) [1-18]. There is comparatively little data in the available literature on changes in the spectrum (pool, fund) of free plasma amino acids against the background of atherosclerosis. Only a few works are devoted to a comparative assessment and interpretation of changes in the pool of free amino acids at different stages of atherosclerosis and in the dynamics of its treatment [12,19].

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